Phage tablets were produced by (i) spray drying of phages, (ii) direct compression of the phage powders into tablets, and then (iii) tablet coating. In this study, Pseudomonas-targeting phage PEV20 was used as a model to produce tablets suitable for oral delivery by utilising industry-scale tablet compression and tablet coating machines. Solid oral dosage forms (i.e., tablets) have the potential to effectively deliver viable phages to the gastrointestinal tract, but formulation studies have been scarce. Phage therapy is an attractive alternative or supplementary therapy to antibiotics as it not only kills multidrug-resistant bacteria, but also minimises the disruption of gut microflora. While the equipment has become more sophisticated and complicated, the need for measuring, monitoring, and recording the states of the coated surfaces, equipment, and substrates (targets) through the use of laser displacement sensor, cameras, and sensors has also increased.Intestinal Pseudomonas aeruginosa is highly problematic in immunocompromised patients such as those in intensive care units in hospitals. In recent years, some devices have adopted cassette-type rollers to make changing coating conditions easier. One of the problems of operating roll coaters is the sizable equipment necessary for large dimensions of the substrates, and the extensive changeover work required. Functional films for optical products (organic ELs, TFT LCDs, touch panels, etc.) Light control (LR) films, anti-reflection (AR) films, anti-glare (AG) films, polarizing films, TAC films, light diffusion films, hard coat (screen protection) films, transparent conductive (ITO) films, index matching films, optical clear adhesive (OCA) films, flexible printed circuits (FPC), prism sheets Secondary batteries and solar cells Secondary battery electrode plates, secondary battery separators, reflector films, light-shielding films, photoresist films, decorative films, window films, heat dissipating films, solar cell back sheets, thin-profile battery laminates Electronic components and semiconductors Flexible printed circuits (FPC), photoresist films, polyimide (PI) films, laminated ceramic capacitors Other functional films and sheets (automobile, housing, fabric, medical, etc.) Leather sheets, carbon fiber products, airbags, heat insulation sheets, wallpaper, cushion flooring (CF), prepreg, non-woven fabrics, felt, mats, carpeting, waterproof moisture permeable sheets, adhesive tapes, transdermal absorption medicine sheets, barrier packaging films Development and trends of systems The demand for mass production using thin film coating technology has been growing as a result of thinner and more functional smartphones and tablets, the miniaturization and increased density of their components, the expanding demands for secondary batteries and solar cells, and the advanced performance of automobiles, construction materials, and fabrics. The section describes a variety of materials and end products that require coating technology. In addition to the above, many different coaters and combinations have been used to achieve smooth coating and pattern printing with high accuracy and at high speeds under various conditions. In some cases, the process is performed in a clean room to prevent the adhesion of foreign particles on the wet surface before solidification.
These systems are mainly used for wet coating.
However, wide and long substrates (targets) can also be coated continuously and quickly. In general, use is limited to the coating of relatively thin flat targets such as films and sheets. As a result, roll coaters have been adopted in various industrial fields, including electronic components, optical and LCD products, food, and medicine. Coating systems that use rollers are able to support various coating fluid viscosities and different coating thicknesses through the combination and specialization of many different technologies. Roll coater systems are used for coating flat targets (substrates) through a combination of multiple different rollers to obtain the desired coated surface.
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